Extending the lifespan of red blood cells: advanced age, alcoholism, splenectomy, iron deficiency, folate or vit.Vitamin C or vitamin E: abnormal Hb glycation.Hb structural changes : the presence of Hb S (sickle cell disease) or Hb C will underestimate the HbA1c value.The presence of reticulocytes (relatively immature red blood cells): in the event of haemolysis, acute anemia or chronic liver disease, but also treatment with iron, erythropoietin, vitamin B12 and certain antiviral drugs, or a recent transfusion.However, ask your doctor if other tests will be done at the same time and if you should prepare for them. You don't have to do anything special to prepare for your A1C test(fasting is not necessary). Routinely, the most reliable assay method is high performance liquid chromatography (HPLC) (the reference method is mass spectrometry, an expensive method, reserved for only a few laboratories) The A1C test test is performed in a medical laboratory using a blood sample from a finger or your arm Note : Younger people have more years ahead of them with diabetes, so their goal may be lower to reduce the risk of complications, unless they often suffer from low blood sugar. A person who has had diabetes that has not been treated for a long time may have a rate higher than 8%.
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